Functional roles of plasma membrane localized estrogen receptors.
Indian J Exp Biol
;
2003 Jul; 41(7): 740-7
Article
in English
| IMSEAR
| ID: sea-57858
ABSTRACT
A series of emerging data supports the existence and importance of plasma membrane localized estrogen receptors in a variety of cells that are targets for the steroid hormone action. When estradiol (E2) binds to the cell surface protein, the ensuing signal transduction event triggers downstream signaling cascades that contribute to important biological functions. Aside from the classical signaling through nuclear estrogen receptors, we have provided evidence for the functional roles of an estrogen receptor localized in the plasma membrane. This review highlights some of the recent advances made in the understanding of the genomic/non-genomic actions of plasma membrane localized estrogen receptors.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Humans
/
Signal Transduction
/
Receptors, Estrogen
/
Cell Membrane
/
Estradiol
/
Animals
Language:
English
Journal:
Indian J Exp Biol
Year:
2003
Type:
Article
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