Influence of ethanolic extract of Tephrosia purpurea Linn. on mast cells and erythrocytes membrane integrity.
Indian J Exp Biol
;
2000 Aug; 38(8): 837-40
Article
in English
| IMSEAR
| ID: sea-57936
ABSTRACT
The ethanolic extract of T. purpurea Linn. was studied for its in vitro effect on rat mast cell degranulation and erythrocyte membrane integrity in vitro. The extract in concentration of 25-200 microg/ml showed a dose-dependant inhibition of rat mast cell degranulation induded by compound 48/80 and egg albumin. T. purpurea extract was found to inhibit haemolysis of erythrocytes induced by hypotonic solution but accelerated haemolysis induced by heat at a concentration of 100 microg/ml. The studies reveal that the ethanolic extract of T. purpurea may inhibit degranulation of mast cells by a mechanism other than membrane stabilization.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rats
/
Humans
/
Plant Extracts
/
Cell Degranulation
/
Rats, Wistar
/
Ethanol
/
Erythrocyte Membrane
/
Fabaceae
/
Animals
/
Mast Cells
Language:
English
Journal:
Indian J Exp Biol
Year:
2000
Type:
Article
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