Pharmacological actions of Abies pindrow Royle leaf.
Indian J Exp Biol
;
1998 Feb; 36(2): 187-91
Article
in English
| IMSEAR
| ID: sea-58037
ABSTRACT
Petroleum ether (PE), benzene (BE), chloroform (CE), acetone (AE) and ethanolic (EE) extracts (50-200 or 200 mg/kg, i.p. or 200 mg/kg, p.o.) of dried Abies pindrow leaves, given 30-45 min before showed significant anti-inflammatory (both against acute and sub-acute models), analgesic, barbiturate hypnosis potentiation and anti-ulcerogenic acitivities in rats. All the extracts except EE decreased swim stress immobility in mice indicating some degree of anti-depressant activity. Only PE exhibited hypotension in dogs blocked by atropine. Chemically, extracts showed the presence of glycosides, steroids, terpenoids and flavonoids. They had no anti-bacterial effect. However, toxicity studies indicated that the extracts had an extended safety index. The investigations are consonant with some of the uses of this plant in Ayurveda.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Plants, Medicinal
/
Rats
/
Female
/
Male
/
Plant Extracts
/
Cardiovascular Agents
/
Anti-Inflammatory Agents, Non-Steroidal
/
Plant Leaves
/
Dogs
/
Analgesics
Language:
English
Journal:
Indian J Exp Biol
Year:
1998
Type:
Article
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