Increased degradation of dermal collagen in diabetic rats.
Indian J Exp Biol
;
1991 Nov; 29(11): 1081-3
Article
in English
| IMSEAR
| ID: sea-58106
ABSTRACT
The effect of alloxan induced diabetes on the dermal collagen content of albino rats was studied in relation to few lysosomal enzymes. Diabetes decreased the dermal collagen content. The specific activities of the lysosomal enzymes studied in the diabetic rat skin were elevated. It has been established that lysosomal enzymes degrade the connective tissue components. Thus, it may be suggested that the increase in the lysosomal enzymes studied should have facilitated the decrease in dermal collagen content of diabetic rats by increasing the degradation of dermal collagen.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rats
/
Rats, Inbred Strains
/
Skin
/
Male
/
Collagen
/
Diabetes Mellitus, Experimental
/
Animals
Language:
English
Journal:
Indian J Exp Biol
Year:
1991
Type:
Article
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