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Recombinant mycobacterial proteins future directions to improve protective efficacy.
Indian J Exp Biol ; 2001 Dec; 39(12): 1214-9
Article in English | IMSEAR | ID: sea-58107
ABSTRACT
A large number of subunit vaccine candidates have recently been developed as alternatives to Mycobacterium bovis Bacillus Calmette-Guerin (BCG), which gives unpredictable and highly variable protection against tuberculosis. Immunological potential of various recombinant proteins against mycobacterial infections has been discussed. Further, strategies have been suggested, which include development of constructs coexpressing cytokines or regimens utilizing recombinant proteins for further improving the protective efficacy.
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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Species Specificity / Bacterial Proteins / Recombinant Proteins / Humans / Protein Processing, Post-Translational / Amino Acid Sequence / Animals / Mice / Mycobacterium Language: English Journal: Indian J Exp Biol Year: 2001 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Species Specificity / Bacterial Proteins / Recombinant Proteins / Humans / Protein Processing, Post-Translational / Amino Acid Sequence / Animals / Mice / Mycobacterium Language: English Journal: Indian J Exp Biol Year: 2001 Type: Article