Anticonvulsant potential of holy basil, Ocimum sanctum Linn., and its cultures.
Indian J Exp Biol
;
2003 Nov; 41(11): 1329-33
Article
in English
| IMSEAR
| ID: sea-58222
ABSTRACT
Callus cultures from stem of O. sanctum were induced on slightly modified Murashige and Skoog's (MS) medium and supplemented with 2,4-dichlorophenoxyacetic acid (2,4-D, 1-2 ppm) and kinetin (kn, 1 ppm). Different extractives of stem, leaf and stem callus of O. sanctum were tested for anticonvulsant activity against standard drug phenytoin using maximal electroshock (MES) model. Ethanol and chloroform extractives of stem, leaf and stem calli were effective in preventing tonic convulsions induced by transcorneal electroshock.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Phenytoin
/
Seizures
/
Plant Extracts
/
Plant Stems
/
Ocimum
/
Dose-Response Relationship, Drug
/
Electroshock
/
Animals
/
Phytotherapy
/
Mice
Language:
English
Journal:
Indian J Exp Biol
Year:
2003
Type:
Article
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