Production of heptaene antifungal antibiotic by Streptomyces purpeofuscus CM 1261.

Jain, Praveen Kumar; Jain, P C

Jain, Praveen Kumar; Jain, P C.

Indian J Exp Biol ; 2005 Apr; 43(4): 342-5

Article in English | IMSEAR | ID: sea-58472

ABSTRACT

ABSTRACT

A strain of Streptomyces purpeofuscus CM 1261 isolated from a sample of compost collected locally was found to possess strong antagonistic activity against 4 human pathogenic fungi i.e., Candida albicans, Aspergillus niger, Microsporum gypseum and Trichophyton sp. The active antifungal compound produced by it was found to be a heptaene group of polyene antifungal antibiotic.

Subject(s)

Antifungal Agents/isolation & purification; Aspergillus niger/drug effects; Candida albicans/drug effects; Microbial Sensitivity Tests; Microsporum/drug effects; Mitosporic Fungi/drug effects; Polyenes; Streptomyces/metabolism; Trichophyton/drug effects

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Polyenes / Aspergillus niger / Streptomyces / Trichophyton / Candida albicans / Microbial Sensitivity Tests / Mitosporic Fungi / Microsporum / Antifungal Agents Language: English Journal: Indian J Exp Biol Year: 2005 Type: Article

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