Renoprotective effect of grape seeds extract in ethylene glycol induced nephrotoxic mice.

Mohanasundari, M; Sabesan, M; Sethupathy, S

Mohanasundari, M; Sabesan, M; Sethupathy, S.

Indian J Exp Biol ; 2005 Apr; 43(4): 356-9

Article in English | IMSEAR | ID: sea-58514

ABSTRACT

ABSTRACT

Grape seed extract treatment in ethylene glycol (EG) induced nephrotoxic mice improved antioxidant status and significantly decreased urinary lactate dehydrogenase (LDH) and lipid peroxidation. The extract rendered antioxidant protection against oxidative stress induced by EG and may help in protecting renal tissue against EG toxicity.

Subject(s)

Animals; Antioxidants/isolation & purification; Disease Models, Animal; Ethylene Glycol/toxicity; Kidney/drug effects; Kidney Diseases/chemically induced; Lipid Peroxidation/drug effects; Mice; Plant Extracts/isolation & purification; Seeds/chemistry; Vitis/chemistry

Fulltext

XML

Search on Google

Full text: Available Index: IMSEAR (South-East Asia) Main subject: Seeds / Plant Extracts / Lipid Peroxidation / Ethylene Glycol / Vitis / Disease Models, Animal / Kidney / Kidney Diseases / Animals / Mice Language: English Journal: Indian J Exp Biol Year: 2005 Type: Article

Similar

MEDLINE

LILACS

LIS

Fulltext

XML

Search on Google