Immunopotentiating activity of septilin.
Indian J Exp Biol
;
1997 Dec; 35(12): 1319-23
Article
in English
| IMSEAR
| ID: sea-58942
ABSTRACT
Oral administration of septilin (100mg/animal/dose; five doses) was found to enhance natural killer cell mediated cytotoxicity and antibody-dependent cellular cytotoxicity in normal mice as well as tumour-bearing mice. Septilin treatment also activated the peritoneal macrophages which produced cytotoxicity to L929 cells. Septilin increased proliferation of bone-marrow cells and there was an increase in the number of alpha-naphthyl acetate esterase staining cells in the bone-marrow. In addition to the activation of cellular immunity, septilin was found to increase the number of antibody producing cells in the spleen and activation of antibody-dependent complement-mediated cell lysis. These studies justifies the use of this herbal preparation in improving immunocompetence in disease states.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Bone Marrow Cells
/
Plant Extracts
/
Killer Cells, Natural
/
Adjuvants, Immunologic
/
Anti-Inflammatory Agents, Non-Steroidal
/
Administration, Oral
/
Animals
/
Mice
/
Antibody Formation
Language:
English
Journal:
Indian J Exp Biol
Year:
1997
Type:
Article
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