Steroid hormones retard aflatoxin-induced cytotoxicity.
Indian J Exp Biol
;
1993 Sep; 31(9): 780-1
Article
in English
| IMSEAR
| ID: sea-59354
ABSTRACT
Protective effect of sex steroid hormones on aflatoxin-induced cytotoxicity on RBC (hemolysis) was examined in vitro. Addition of aflatoxin (2 micrograms/ml) in RBC suspension caused significant increase in hemolysis. Concurrent addition of aflatoxin (2 micrograms/ml) and estradiolbenzoate (100-1200 pg/ml) in RBC suspension significantly retarded aflatoxin-induced hemolysis. Similarly, addition of aflatoxin (2 micrograms/ml) along with testosterone propionate (5-60 ng/ml) in RBC suspension retarded aflatoxin-induced hemolysis. Among the two synthetic hormones studied estradiolbenzoate was more potent than testosterone propionate.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Testosterone
/
Humans
/
Adult
/
Aflatoxins
/
Estradiol
/
Hemolysis
Language:
English
Journal:
Indian J Exp Biol
Year:
1993
Type:
Article
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