A synthetic decapeptide analogue of human seminal plasma inhibin exhibiting specific suppression of follicle stimulating hormone release in rats.
Indian J Exp Biol
;
1989 Jan; 27(1): 10-3
Article
in English
| IMSEAR
| ID: sea-59494
ABSTRACT
Synthesis and biological profile of a decapeptide analogue, [Tyr85, Cys(Acm)87]85-94 of human seminal plasma inhibin (HSPI) are described. The peptide suppressed the circulatory levels of follicle stimulating hormone (FSH) in adult male rats. No change in the levels of luteinizing hormone (LH) and prolactin (Prl) was observed. Whereas the peptide suppressed the release of both FSH and LH in vitro. This decapeptide is the smallest peptide reported so far to have FSH suppressing activity.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Peptide Fragments
/
Prolactin
/
Rats
/
Male
/
Luteinizing Hormone
/
Proteins
/
Chromatography, High Pressure Liquid
/
Seminal Plasma Proteins
/
Prostatic Secretory Proteins
/
Follicle Stimulating Hormone
Language:
English
Journal:
Indian J Exp Biol
Year:
1989
Type:
Article
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