P-aminodiphenylamine induced biochemical changes in sex organs of male albino rats.
Indian J Exp Biol
;
1992 Feb; 30(2): 110-3
Article
in English
| IMSEAR
| ID: sea-59579
ABSTRACT
Intraperitoneal administration of p-aminodiphenylamine (p-ADPA), an aromatic amine of wide industrial applications, / 42.5 mg/kg body weight for 180 days significantly decreased the activities of testicular lactate dehydrogenase and hyaluronidase and lactic acid content indicating arrest of spermatogenesis. Patchy necrosis of the testis was confirmed histopathologically. No change in testicular cholesterol, fructose content of coagulating glands and dorso-lateral prostate and activities of alkaline phosphatase in seminal vesicle and acid phosphatase in ventral prostate support normal androgenic status.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Phenylenediamines
/
Rats
/
Rats, Inbred Strains
/
Male
/
Proteins
/
Cholesterol
/
Genitalia, Male
/
Hyaluronoglucosaminidase
/
L-Lactate Dehydrogenase
/
Animals
Language:
English
Journal:
Indian J Exp Biol
Year:
1992
Type:
Article
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