Effect of experimental diabetes on the activities of hexokinase, glucose-6-phosphate dehydrogenase and catecholamines in rat erythrocytes of different ages.
Indian J Exp Biol
;
1997 Jul; 35(7): 792-5
Article
in English
| IMSEAR
| ID: sea-59633
ABSTRACT
Hexokinase and glucose-6-phosphate dehydrogenase were assayed in various circulating age fractions i.e., young, middle-aged and old red cell from control, diabetic and insulin-treated diabetic rats. An increase in the activity of hexokinase was observed in three age-wise separated fractions of red cells from diabetic animals in comparison to control. The activity of glucose-6-phosphate dehydrogenase on the other hand decreased in separated ageing fractions of diabetic red cells when compared to control. Reversal of these two enzymes were observed in insulin-treated diabetic rats. The levels of glycosylated haemoglobin and catecholamines were found to increase with ageing red cells in controls and also increased in red cells plasma.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rats
/
Female
/
Catecholamines
/
Rats, Wistar
/
Diabetes Mellitus, Experimental
/
Erythrocyte Aging
/
Glucosephosphate Dehydrogenase
/
Hexokinase
/
Animals
Language:
English
Journal:
Indian J Exp Biol
Year:
1997
Type:
Article
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