Effect of thyroidectomy on fast and slow muscle fibres of rat gastrocnemius muscle.
Indian J Exp Biol
;
2000 Jun; 38(6): 575-9
Article
in English
| IMSEAR
| ID: sea-60158
ABSTRACT
A combined histochemical, biochemical and electrophoretic study with respect to the enzymes succnic dehydrogenase(SDH), myofibrillar adenosine triphosphatase (m-ATPase), lactate dehydrogenase (LDH) isozymes and myosin light chains was carried out to investigate the response of rat gastrocnemius muscle (medial head). Twelve weeks after thyroidectomy, the results indicated a shift from fast to slow type pattern of LDH isozymes, fibre type transformation from Type II to Type I and a decrease in SDH and m-ATPase activity. The results suggest, possible thyroidal involvement in determining the phenotypic properties of skeletal muscle.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rats
/
Succinate Dehydrogenase
/
Thyroidectomy
/
Male
/
Adenosine Triphosphatases
/
Muscle Fibers, Slow-Twitch
/
Muscle Fibers, Fast-Twitch
/
Myosin Light Chains
/
Hypothyroidism
/
Isoenzymes
Language:
English
Journal:
Indian J Exp Biol
Year:
2000
Type:
Article
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