Influence of haloperidol on testicular functions in rat.
Indian J Exp Biol
;
1997 Sep; 35(9): 1014-5
Article
in English
| IMSEAR
| ID: sea-60204
ABSTRACT
The study involved exploration of the role of dopamine antagonist haloperidol on the testicular functions of rat. Chronic administration of haloperidol (0.2 mg/kg/day/sc for 21 days) caused significant increase in brain DA and serum prolactin. At testicular level the treatment revealed atrophic degeneration of seminiferous epithelium indicating suppression of hypophyseal gonadotrophins and proves importance of dopaminergic control over prolactin release for normal functions of male gonad.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rats
/
Testis
/
Male
/
Rats, Sprague-Dawley
/
Dopamine Antagonists
/
Haloperidol
/
Animals
Language:
English
Journal:
Indian J Exp Biol
Year:
1997
Type:
Article
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