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Penicillic acid as Na+,K+ and Ca2+ channel blocker in isolated frog's heart at toxic levels.
Indian J Exp Biol ; 1990 Mar; 28(3): 295-6
Article in English | IMSEAR | ID: sea-60419
ABSTRACT
The effect of penicillic acid on isolated frog's heart has been studied along with ions of Na+,K+ and Ca2+. Penicillic acid has been found to inhibit the entry of these ions into cardiac tissue thereby arresting the action of the heart. The blockage can be washed away by perfusion with Ringer's solution.
Subject(s)
Full text: Available Index: IMSEAR (South-East Asia) Main subject: Penicillic Acid / Ranidae / Caproates / Calcium Channels / Potassium Channels / Sodium Channels / Heart / Animals Language: English Journal: Indian J Exp Biol Year: 1990 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Penicillic Acid / Ranidae / Caproates / Calcium Channels / Potassium Channels / Sodium Channels / Heart / Animals Language: English Journal: Indian J Exp Biol Year: 1990 Type: Article