Effect of Asteracantha longifolia Nees. against CCl4 induced liver dysfunction in rat.

Shailajan, Sunita; Chandra, Naresh; Sane, R T; Menon, Sasikumar

Shailajan, Sunita; Chandra, Naresh; Sane, R T; Menon, Sasikumar.

Indian J Exp Biol ; 2005 Jan; 43(1): 68-75

Article in English | IMSEAR | ID: sea-60600

ABSTRACT

ABSTRACT

Significant recovery after treatment with the whole plant slurry of A.longifolia Nees. was observed in plasma AST, ALT and cholesterol levels in CCl4 induced hepatotoxic rats. This was amply supported by electron micrographs, which indicated normalization of cytoarchitecture of mitochondria and endoplasmic reticulum. The results suggest that the slurry of the plant is useful as a liver tonic.

Subject(s)

Acanthaceae/chemistry; Animals; Carbon Tetrachloride/toxicity; Female; Liver/drug effects; Liver Diseases/chemically induced; Liver Function Tests; Male; Microscopy, Electron; Plant Extracts/therapeutic use; Plant Leaves/chemistry; Protective Agents/therapeutic use; Rats; Rats, Wistar; Seeds/chemistry; Silymarin/therapeutic use

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Rats / Seeds / Silymarin / Female / Male / Carbon Tetrachloride / Plant Extracts / Microscopy, Electron / Rats, Wistar / Plant Leaves Language: English Journal: Indian J Exp Biol Year: 2005 Type: Article

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