'Dark' cell formation under protein malnutrition: process of conversion and concept of 'semi-dark' type Purkinje cells.
Indian J Exp Biol
;
1992 Jun; 30(6): 470-3
Article
in English
| IMSEAR
| ID: sea-60781
ABSTRACT
This paper deals with some deleterious effects of protein malnourishment in rat cerebellum. Severe protein deprivation enhanced the formation of 'dark' cells in white rats. It is postulated that abnormal changes in the neuronal contents induced by nutritional stress play a vital role in the formation of the 'dark' cells through an intermediary stage, 'semi-dark' cells. Centrophenoxine a lipofuscinolytic agent, however, seems to interfere with the process of formation of 'dark' cells and/or helps reconversion of the 'dark' cells into the normal or 'light' type Purkinje cells.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Protein Deficiency
/
Purkinje Cells
/
Rats
/
Rats, Inbred Strains
/
Meclofenoxate
/
Lipofuscin
/
Animals
Language:
English
Journal:
Indian J Exp Biol
Year:
1992
Type:
Article
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