Influence of parathyroidectomy on liver glycogen in rats treated with carbon tetrachloride.
Indian J Exp Biol
;
1990 Aug; 28(8): 794-5
Article
in English
| IMSEAR
| ID: sea-60799
ABSTRACT
Carbon tetrachloride (CCl4) brings about a rise in cytosolic free calcium which may lead to glycogen mobilization. Therefore, glycogen and glucose-6-phosphatase (G-6-pase) levels in the liver of parathyroidectomized (PTX) rats following CCl4 treatment have been estimated. CCl4 depletes both glycogen and G-6-pase levels in the liver. PTX followed by CCl4 administration, however, fails to restore liver glycogen and G-6-pase levels. The results suggest that neither cytosolic Ca2+ nor phospholipase A2 mediation is needed for glycogen mobilization, however, glucocorticoid intervention might have a role in such mechanisms.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Parathyroid Glands
/
Rats
/
Rats, Inbred Strains
/
Male
/
Carbon Tetrachloride Poisoning
/
Chemical and Drug Induced Liver Injury
/
Gluconeogenesis
/
Hypocalcemia
/
Liver Glycogen
/
Animals
Language:
English
Journal:
Indian J Exp Biol
Year:
1990
Type:
Article
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