Effect of aqueous extract from Nigella sativa L. on guinea pig isolated heart.

Shafei, Mohammad Naser; Boskabady, Mohammad Hossein; Parsaee, Heydar

Shafei, Mohammad Naser; Boskabady, Mohammad Hossein; Parsaee, Heydar.

Indian J Exp Biol ; 2005 Jul; 43(7): 635-9

Article in English | IMSEAR | ID: sea-60828

ABSTRACT

ABSTRACT

A potent inhibitory effect of aqueous extract from N. sativa on calcium channel of guinea pig heart was found comparable and even greater than that of diltazem. The results may also indicate an opening effect for the plant on potassium channel of isolated heart.

Subject(s)

Animals; Calcium Channel Blockers/pharmacology; Calcium Channels/drug effects; Diltiazem/pharmacology; Female; Guinea Pigs; Heart/drug effects; Heart Rate/drug effects; Male; Myocardial Contraction/drug effects; Myocardium/metabolism; Nigella sativa; Plant Extracts/pharmacology; Potassium Channels/drug effects; Water

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Female / Male / Water / Plant Extracts / Calcium Channel Blockers / Diltiazem / Calcium Channels / Potassium Channels / Nigella sativa / Guinea Pigs Language: English Journal: Indian J Exp Biol Year: 2005 Type: Article

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