Insecticide induced disruptions in functioning of developing brain of Rana cyanophlictis.
Indian J Exp Biol
;
1992 Aug; 30(8): 701-4
Article
in English
| IMSEAR
| ID: sea-60866
ABSTRACT
Synthetic pyrethroid insecticide permethrin significantly decreased the levels of regulatory proteins (S-100 and calmodulin) in the developing CNS of tadpoles of R. cyanophlictis. Remarkable inhibition of enzymes acetylcholinesterase and choline acetylase and significant accumulation of neurotransmitter acetylcholine were observed in permethrin treated animals. Permethrin exposure significantly decreased the activity of phosphodiesterase. The results support molecular disruptions occurring due to permethrin induced toxicity. This in turn may bring about neuronal inefficiency in the treated tadpoles.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Pyrethrins
/
Ranidae
/
Brain
/
Proteins
/
Permethrin
/
Insecticides
/
Animals
Language:
English
Journal:
Indian J Exp Biol
Year:
1992
Type:
Article
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