Evidence for presence of GABA-ergic receptor mediated dispersion in isolated scale melanophores of a carp, Cirrhinus mrigala Ham.
Indian J Exp Biol
;
2002 Jan; 40(1): 78-82
Article
in English
| IMSEAR
| ID: sea-60885
ABSTRACT
Effects of GABA-ergic agonists and antagonists were examined on the melanophores of a carp C. mrigala in vitro. GABA and baclofen both induced concentration - related dispersion in fish melanophores. Denervation of the melanophores by reserpine treatment potentiated the sensitivity of the melanophores to GABA. While denervation by cooling treatment inhibited the sensitivity of the melanophores to GABA, atropine, bicuculline and pentylenetetrazole all inhibited the dispersal responses of the melanophores induced by higher concentrations of GABA. 5-aminovaleric acid also significantly inhibited the dispersion of the melanophores induced either by GABA or baclofen. It is concluded that GABA-ergic agonist induced dispersal responses in C mrigala melanophores are mediated through specific GABA receptors. The presence of both GABAA and GABAB receptors in this fish melanophores has been indicated.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Bicuculline
/
Female
/
Male
/
Carps
/
Receptors, GABA-B
/
Receptors, GABA-A
/
Muscarinic Antagonists
/
GABA Antagonists
/
GABA Agonists
/
Adrenergic Uptake Inhibitors
Language:
English
Journal:
Indian J Exp Biol
Year:
2002
Type:
Article
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