Testosterone and lipid peroxide metabolism in orchidectomised rats.

ABSTRACT

The effect of testosterone on lipid peroxides and antiperoxidative enzymes in normal and orchidectomised animals has been studied. Orchidectomy results in increased lipid peroxidation in the heart, while administration of testosterone to the animals reverses this to a certain extent. On the other hand the administration of testosterone to normal rats results in increased lipid peroxidation in the liver and heart.