Effect of fish oil on mitochondrial respiration in isoproterenol induced myocardial infarction in rats.
Indian J Exp Biol
;
2002 Mar; 40(3): 268-72
Article
in English
| IMSEAR
| ID: sea-61308
ABSTRACT
Following isoproterenol treatment mitochondrial lipid peroxidation, phosphoslipase activity, lactate and calcium increased significantly, while activities of tricarboxylic acid cycle enzymes, enzymes of respiratory chain and ATP production showed decline. Oxidative phosphorylation was also affected on isoproterenol treatment with significant reduction in all the variables. Fish oil pretreatment in isoproterenol treated rats showed improved mitochondrial energy metabolism. The results suggest cardioprotective effect of fish oil.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Oxygen Consumption
/
Rats
/
Male
/
Fish Oils
/
Lipid Peroxidation
/
Rats, Wistar
/
Isoproterenol
/
Animals
/
Mitochondria, Heart
/
Myocardial Infarction
Language:
English
Journal:
Indian J Exp Biol
Year:
2002
Type:
Article
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