Modulation of humoral immune responses by Tinospora malabarica in experimental animals.

Bhattacharya, S K; Maity, P C; Mediratta, P; Sen, P

Bhattacharya, S K; Maity, P C; Mediratta, P; Sen, P.

Indian J Exp Biol ; 1991 Oct; 29(10): 971-2

Article in English | IMSEAR | ID: sea-61438

ABSTRACT

ABSTRACT

Effect of alkaloidal fraction of aqueous extract of T. malabarica (Tm) was studied on humoral antibody responses in rats and guineapigs. The anti-SRBC haemagglutination titre was found to be enhanced in rats pretreated with Tm (2.5 mg/kg). Passive cutaneous anaphylaxis (PCA) in rats was also increased in Tm treated group. In vitro experiments with sensitized rat peritoneal mast cells showed a significant decrease in antigen-induced various spasmogens on isolated guineapig ileum.

Subject(s)

Animals; Antibody Formation/drug effects; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hemagglutination/drug effects; Histamine Release/drug effects; Male; Mast Cells/metabolism; Passive Cutaneous Anaphylaxis/drug effects; Plant Extracts/pharmacology; Plants, Medicinal; Rats

Fulltext

XML

Search on Google

Full text: Available Index: IMSEAR (South-East Asia) Main subject: Plants, Medicinal / Rats / Female / Male / Passive Cutaneous Anaphylaxis / Plant Extracts / Dose-Response Relationship, Drug / Guinea Pigs / Hemagglutination / Histamine Release Language: English Journal: Indian J Exp Biol Year: 1991 Type: Article

Similar

MEDLINE

LILACS

LIS

Fulltext

XML

Search on Google