Atrial natriuretic peptide prevents bronchoconstriction in vitro.
Indian J Exp Biol
;
1997 Feb; 35(2): 197-9
Article
in English
| IMSEAR
| ID: sea-61524
ABSTRACT
Under in vitro conditions atrial natriuretic peptide (ANP) caused specific relation of bronchoconstriction induced by tosyl arginine methyl ester (TAME) on rat trachea. This supports the hypothesis that ANP is a relaxant of airway as well as vascular smooth muscle and since lung tissue contains ANP and ANP receptors, it is hypothesized that the lungs may be a target organ for ANP. It is concluded that ANP had definite bronchodilating properties on rat trachea mounted in vitro and could be a possible antagonist of TAME.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rats
/
Tosylarginine Methyl Ester
/
Bronchoconstriction
/
Atrial Natriuretic Factor
/
Rats, Sprague-Dawley
/
Animals
Language:
English
Journal:
Indian J Exp Biol
Year:
1997
Type:
Article
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