Alterations in large gut associated lymphatic tissues (LGALT) during experimental colorectal carcinogenesis.
Indian J Exp Biol
;
1993 Oct; 31(10): 793-6
Article
in English
| IMSEAR
| ID: sea-61794
ABSTRACT
Alterations in large gut associated lymphatic tissues (LGALT) were studied histologically during 20-methylcholanthrene (MCA) induced colorectal carcinogenesis. Precancerous changes in LGALT included hyperplasia, hyperchromasia of lymphocytes and enlargement of lymphoid follicles. In addition, follicular invasion in muscular layer and cellular disorganization of diffuse lymphatic tissues were observed in neoplasia. Since, LGALT showed remarkable changes during carcinogenesis, this aspect may be considered during assessment of preneoplastic lesions, along with other histologic features of early neoplasia.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Precancerous Conditions
/
Rats
/
Male
/
Colorectal Neoplasms
/
Rats, Sprague-Dawley
/
Intestine, Large
/
Lymphoid Tissue
/
Animals
/
Methylcholanthrene
Language:
English
Journal:
Indian J Exp Biol
Year:
1993
Type:
Article
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