Toxigenicity of Edwardsiella tarda isolates of fish and pig origin in experimental models.
Indian J Exp Biol
;
1996 Dec; 34(12): 1254-6
Article
in English
| IMSEAR
| ID: sea-61919
ABSTRACT
Indian isolates of E. tarda from fish (7) and pigs (2) were examined for their enterotoxigenicity/cytotoxigenicity in rabbit ligated ileal loop (RLIL), suckling mouse, rabbit skin and Vero cell monolayers. Cell free culture filtrates (CFCF) of isolates from fish and pigs, induced blood tinged fluid accumulation in RLIL, increased vasopermeability in rabbit skin, and caused cytopathic effect in Vero cells but could not induce fluid accumulation in suckling mouse. CFCFs lost their activity on heating at 63 degrees C for 30 min or 72 degrees C for 15 sec, and also at pH < or = 4.5 or > or = 8.5. The toxic factor was released extracellularly and was nondializable.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rabbits
/
Swine
/
Bacterial Toxins
/
Vero Cells
/
Capillary Permeability
/
Cells, Cultured
/
Chlorocebus aethiops
/
Enterobacteriaceae
/
Enterobacteriaceae Infections
/
Fishes
Type of study:
Prognostic study
Language:
English
Journal:
Indian J Exp Biol
Year:
1996
Type:
Article
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