Renal beta-glucuronidase activity is a bioassay of serum testosterone levels in rats.
Indian J Exp Biol
;
1996 Jun; 34(6): 582-3
Article
in English
| IMSEAR
| ID: sea-61947
ABSTRACT
Alteration in the testosterone levels in experimental animals is reflected by a corresponding change in kidney beta-glucuronidase activity. With a view to use change in renal beta-glucuronidase activity as a bioassay of androgens, the activity of renal beta-glucuronidase and serum testosterone levels were determined following treatment with cisplatin for 3 alternate days. Levels of both renal beta-glucuronidase activity and serum testosterone were significantly decreased in cisplatin-treated rats. It is therefore suggested that kidney beta-glucuronidase activity can be used as a bioassay of androgens.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rats
/
Testosterone
/
Biological Assay
/
Male
/
Rats, Wistar
/
Glucuronidase
/
Kidney
/
Animals
Language:
English
Journal:
Indian J Exp Biol
Year:
1996
Type:
Article
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