Polyclonal B-lymphocyte activation of sheep by Mycobacterium phlei against sheep pox virus.
Indian J Exp Biol
;
1992 Mar; 30(3): 247-9
Article
in English
| IMSEAR
| ID: sea-62026
ABSTRACT
A trypsinized preparation of Mycobacterium phlei, non specific stimulator of immunity (NSI), and Sheep Pox Virus (SPV) were inoculated in different groups of sheep to activate B-lymphocytes and induce SPV neutralizing substance(s). NSI sensitized sheep B-lymphocytes in the presence of NSI or lymphokine elaborated SPV neutralizing substance(s). The SPV sensitized B-lymphocytes also mediated such neutralizing substance(s). Healthy control sheep B-lymphocytes failed to show any appreciable amount of viral neutralizing substance. However, a significant virus neutralizing substance(s) was detected when healthy sheep B-lymphocytes were cultured in presence of NSI antigen along with lymphokines.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Poxviridae
/
Female
/
Male
/
Sheep
/
Membrane Glycoproteins
/
B-Lymphocytes
/
Lymphocyte Activation
/
Antigens, Differentiation, Myelomonocytic
/
Cell Adhesion Molecules
/
Vaccination
Language:
English
Journal:
Indian J Exp Biol
Year:
1992
Type:
Article
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