Tumor necrosis factor alpha and interleukin 6 in infants with sepsis.
Indian Pediatr
;
2005 Oct; 42(10): 1024-8
Article
in English
| IMSEAR
| ID: sea-6209
ABSTRACT
Thirty-two infants above one month of age admitted to a tertiary care hospital with signs of infection and presumptive diagnosis of sepsis were included. Cytokine levels of tumor necrosis factor alpha (TNFmu) and interleukin-6 (IL 6) were estimated at admission and after 48 to 72 hr, and their relationship examined to the outcome. Significantly higher TNFalpha and IL-6 levels were seen in infants with sepsis compared to control. The TNFalpha levels significantly decreased in patients with sepsis, septic shock and the survivors, while the patients who did not survive, the levels showed no significant change after 48 hr. The initial levels of IL6 were comparatively higher in patients with septic shock and non-survivors, and increased at 48 hr of admission in patients with sepsis, septic shock and non-survivors.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Prognosis
/
Shock, Septic
/
Female
/
Humans
/
Male
/
Biomarkers
/
Case-Control Studies
/
Prospective Studies
/
Interleukin-6
/
Tumor Necrosis Factor-alpha
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Country/Region as subject:
Asia
Language:
English
Journal:
Indian Pediatr
Year:
2005
Type:
Article
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