In vitro antiviral activity of plant extracts on goatpox virus replication.
Indian J Exp Biol
;
2008 Feb; 46(2): 120-7
Article
in English
| IMSEAR
| ID: sea-62223
ABSTRACT
Four plants having known medicinal properties were screened for inhibition of goatpox virus (GTPV) replication in vitro. Of the 4 plants, extract of Acacia arabica (Babul) and Eugenia jambolana (Jamun) leaves had inhibition (%) 99.70 and 99.92 at their maximum non toxic concentrations, 99.93 +/- 0.38 and 1999.73 +/- 0.50 microg/ml, respectively in all cytopathic effect (CPE) inhibition assays. Inhibition of GTPV virus replication was further confirmed by PCR and SYBR Green based quantitative real-time QPCR assays specific for GTPV. Results indicated that the extract of Acacia arabica and Eugenia jambolana leaves inhibited GTPV replication in vitro.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Antiviral Agents
/
Virus Replication
/
Vero Cells
/
Plant Extracts
/
Chlorocebus aethiops
/
Capripoxvirus
/
Poxviridae Infections
/
Plant Leaves
/
Cytopathogenic Effect, Viral
/
Acacia
Language:
English
Journal:
Indian J Exp Biol
Year:
2008
Type:
Article
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