Antigenic structure of foot and mouth disease virus type A22 (Indian isolates).
Indian J Exp Biol
;
1998 Jan; 36(1): 70-5
Article
in English
| IMSEAR
| ID: sea-62291
ABSTRACT
Variations in foot and mouth disease virus are due to amino acid substitutions in the VP1, which is a major immunogen. Analysis of this hypervariable region is essential to know the antigenic structure of the serotype and is necessary to select a suitable vaccine strain. FMDV type A22 is one of the four prevailing virus types for which the vaccine is used regularly. To understand the antigenic structure of this type, carboxy- terminal region of VP1 from two field isolates and vaccine virus were sequenced and analysed. The results indicate that, Indian A22 has distinct antigenic structure.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
DNA, Viral
/
Cattle
/
Molecular Sequence Data
/
Base Sequence
/
Capsid
/
Immunodominant Epitopes
/
Amino Acid Sequence
/
Sequence Homology, Amino Acid
/
Aphthovirus
/
Capsid Proteins
Language:
English
Journal:
Indian J Exp Biol
Year:
1998
Type:
Article
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