Anti-stress and anti-oxidant effects of roots of Chlorophytum borivilianum (Santa Pau & Fernandes).
Indian J Exp Biol
;
2007 Nov; 45(11): 974-9
Article
in English
| IMSEAR
| ID: sea-62631
ABSTRACT
The aqueous extract of C. borivilianum (250 mg/kg for 7 days) significantly reverted the elevated levels of plasma glucose, triglycerides, cholesterol and serum corticosterone and also reduced the ulcer index, adrenal gland weight more as effectively as the standard drug (diazepam) in rats. At 125 mg/kg po, it showed a mild anti-stress activity. Under in vitro 1,1-diphenyl-2-picrylhydrazyl (DPPH*) free radical scavenging assay and lipid peroxidation assay the extract considerably inhibited, in a dose-dependent manner, the levels of DPPH* free radicals and thiobarbituric acid reactive substances, respectively thus showing significant antioxidant property. The results suggested that it could be used for the treatment of oxidative stress-induced disorders.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Organ Size
/
Peptic Ulcer
/
Powders
/
Rats
/
Stress, Psychological
/
Biphenyl Compounds
/
Male
/
Restraint, Physical
/
Plant Extracts
/
Lipid Peroxidation
Language:
English
Journal:
Indian J Exp Biol
Year:
2007
Type:
Article
Similar
MEDLINE
...
LILACS
LIS