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Hypolipidaemic efficacy of Capparis decidua fruit and shoot extracts in cholesterol fed rabbits.
Indian J Exp Biol ; 2005 Oct; 43(10): 863-6
Article in English | IMSEAR | ID: sea-62671
ABSTRACT
High fat diet caused significant (8-fold) increase in serum total cholesterol in rabbits. Administration of C. decidua fruit extract (50% ethanolic) at the dose of 500 mg/kg body weight significantly reduced serum total cholesterol (61%), LDL cholesterol (71%), triglycerides (32%) and phospholipids (25%). Similarly C. decidua shoot extract lowered serum total cholesterol (48%), LDL cholesterol (57%), triglycerides (38%) and phospholipids (36%).The cholesterol content of aorta was decreased by 44 and 28% in fruit and shoot extract treatment respectively. The HDL to total cholesterol ratio and atherogenic index was significantly decreased in plant extract treated groups suggesting antiatherosclerotic nature of these plant extract. These results reveal the hypolipidaemic potential of C. decidua fruit and shoot.
Subject(s)
Full text: Available Index: IMSEAR (South-East Asia) Main subject: Organ Size / Aorta / Phospholipids / Rabbits / Triglycerides / Body Weight / Male / Plant Extracts / Cholesterol / Plant Roots Language: English Journal: Indian J Exp Biol Year: 2005 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Organ Size / Aorta / Phospholipids / Rabbits / Triglycerides / Body Weight / Male / Plant Extracts / Cholesterol / Plant Roots Language: English Journal: Indian J Exp Biol Year: 2005 Type: Article