Acetylhomocysteine thiolactone protection against phosphamidon-induced alteration of regional superoxide dismutase activity in the central nervous system and its correlation with altered lipid peroxidation.
Indian J Exp Biol
;
1992 Sep; 30(9): 850-2
Article
in English
| IMSEAR
| ID: sea-62857
ABSTRACT
Phosphamidon intoxication (2 mg/kg body wt./day for 7 days) inhibited SOD activity, but enhanced the lipid peroxidation in various CNS regions. Administration of cithiolone (8 mg/kg body wt./day, ip for 7 days), however, elevated SOD activity and depleted lipid peroxidation. Interestingly, no significant change was observed either in SOD activity or in lipid peroxidation following simultaneous administration of phosphamidon and cithiolone.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Phosphamidon
/
Rats
/
Superoxide Dismutase
/
Thiophenes
/
Male
/
Lipid Peroxidation
/
Central Nervous System
/
Animals
Language:
English
Journal:
Indian J Exp Biol
Year:
1992
Type:
Article
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