Effect of styrene on testicular enzymes of growing rat.
Indian J Exp Biol
;
1992 May; 30(5): 399-401
Article
in English
| IMSEAR
| ID: sea-62877
ABSTRACT
Effect of styrene (100 or 200 mg/kg body wt/day) for 60 days was observed on testicular enzymes of postnatally maturing rats. A significant decrease in epididymal spermatozoa count was observed only at 200 mg/kg body weight dose. Activities of testicular sorbitol dehydrogenase and acid phosphatase decreased while activities of lactate dehydrogenase, beta-glucuronidase, glucose-6-phosphate dehydrogenase, and gamma-glutamyl transpeptidase significantly increased only in animals exposed to styrene at a dose of 200 mg/kg body weight. The results suggest that exposure to high dose of styrene during developmental period alters the activities of enzymes associated with specific cell type of testis.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rats
/
Sperm Count
/
Styrenes
/
Testis
/
Male
/
Rats, Wistar
/
Styrene
/
Dose-Response Relationship, Drug
/
Animals
Language:
English
Journal:
Indian J Exp Biol
Year:
1992
Type:
Article
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