Experimental hyperthyroidism-induced oxidative stress and impairment of antioxidant defence system in rat testis.
Indian J Exp Biol
;
2005 Nov; 43(11): 1058-67
Article
in English
| IMSEAR
| ID: sea-62992
ABSTRACT
Short-term hyperthyroidism, induced by daily administration of T3 (20 microg/100g body weight) for one, three, and five days consecutively, modulates oxidative stress and antioxidant defence parameters in mitochondrial and postmitochondrial fractions of testis in adult rats. Alteration in antioxidant defences along with oxidative stress parameters in testis by thyroid hormone was found to be associated with a decline in the number of sperms and disturbances in histoarchitecture of seminiferous tubules in the testes; the results indicated that induced hyperthyroid state altered testicular physiology by influencing antioxidant defence system of testes.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rats
/
Superoxide Dismutase
/
Testis
/
Time Factors
/
Body Weight
/
Male
/
Carbon
/
Tissue Distribution
/
Lipid Peroxidation
/
Catalase
Type of study:
Prognostic study
Language:
English
Journal:
Indian J Exp Biol
Year:
2005
Type:
Article
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