Effect of antimicrobials on cholesterol synthesis and content in liver and small intestines.
Indian J Exp Biol
;
1992 Feb; 30(2): 152-4
Article
in English
| IMSEAR
| ID: sea-63051
ABSTRACT
The antimicrobials tetracycline, ampicillin and bactrim (cotrimoxazole) decreased HMG CoA reductase activity in liver and small intestines of albino rats. Diminished incorporation of 1, 2, 14C acetate into cholesterol of small intestines in bactrim group was noted. There was a significant fall in cholesterol content of liver, duodenum, jejunum and ileum of the bactrim group and jejunum only in tetracycline group.
Full text:
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Index:
IMSEAR (South-East Asia)
Main subject:
Rats
/
Tetracycline
/
Trimethoprim, Sulfamethoxazole Drug Combination
/
Cholesterol
/
Ampicillin
/
Hydroxymethylglutaryl CoA Reductases
/
Intestine, Small
/
Liver
/
Animals
Language:
English
Journal:
Indian J Exp Biol
Year:
1992
Type:
Article
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