Effect of carnitine on malondialdehyde, taurine and glutathione levels in heart of rats subjected to myocardial stress by isoproterenol.
Indian J Exp Biol
;
1989 Feb; 27(2): 134-7
Article
in English
| IMSEAR
| ID: sea-63067
ABSTRACT
The effect of carnitine on free fatty acid, malondialdehyde, taurine and glutathione levels in myocardium was studied in rats administered isoproterenol to induce a stress in the myocardium resulting in myocardial ischaemia. Carnitine decreased the levels of free fatty acid and malondialdehyde (an index of lipid peroxidation) when compared to control rats given isoproterenol alone. Taurine and glutathione also registered a fall in the carnitine treated animals when compared to rats treated with isoproterenol alone. The results indicate that carnitine by decreasing the levels of these parameters helps the myocardium to survive from the stress induced by isoproterenol.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rats
/
Rats, Inbred Strains
/
Taurine
/
Male
/
Carnitine
/
Glutathione
/
Heart
/
Isoproterenol
/
Animals
/
Malondialdehyde
Language:
English
Journal:
Indian J Exp Biol
Year:
1989
Type:
Article
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