In vitro antioxidant studies in leaves of Annona species.
Indian J Exp Biol
;
2007 May; 45(5): 480-5
Article
in English
| IMSEAR
| ID: sea-63071
ABSTRACT
Antioxidant potential of leaves of three different species of Annona was studied by using different in vitro models eg., 1,1-diphenyl-2-picryl hydrazyl (DPPH), 2,2-azinobis-(3-ethylbenzothizoline-6-sulphonate) (ABTS), nitric oxide, superoxide, hydroxy radical and lipid peroxidation. The ethanolic extract of A. muricata at 500 microg/ml showed maximum scavenging activity (90.05%) of ABTS radical cation followed by the scavenging of hydroxyl radical (85.88%) and nitric oxide (72.60%) at the same concentration. However, the extract showed only moderate lipid peroxidation inhibition activity. In contrast, the extract of A. reticulata showed better activity in quenching DPPH (89.37%) and superoxide radical (80.88%) respectively. A.squamosa extract exhibited least inhibition in all in vitro antioxidant models excepting hydroxyl radical (79.79%). These findings suggest that the extracts of A. muricata possess potent in vitro antioxidant activity as compared to leaves of A. squamosa and A. reticulata suggesting its role as an effective free radical scavenger, augmenting its therapeutic
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Osmolar Concentration
/
Biphenyl Compounds
/
Goats
/
Plant Extracts
/
Lipid Peroxidation
/
Free Radical Scavengers
/
Plant Leaves
/
Annona
/
Free Radicals
/
Hydrazines
Type of study:
Evaluation studies
/
Prognostic study
Language:
English
Journal:
Indian J Exp Biol
Year:
2007
Type:
Article
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