Role of magnification endoscopy in the diagnosis and evaluation of suspected celiac disease: correlation with histology.
Article
in English
| IMSEAR
| ID: sea-63702
ABSTRACT
BACKGROUND:
Magnification endoscopy (ME), with 115-fold magnification, allows visualization of duodenal villi. We assessed the efficacy of ME for evaluation of villous atrophy.METHODS:
ME and duodenal biopsy were done in 16 patients with suspected celiac disease and 16 control subjects undergoing endoscopy for reflux symptoms. The pathologist was unaware of the ME findings.RESULTS:
Sensitivity, specificity and positive and negative predictive values for villous atrophy (partial or total) were 100%, 91%, 83% and 100%, respectively. Corresponding values for normal villous structure were 91%, 100%, 100% and 83%, respectively. There was significant concordance between the ME and histology findings.CONCLUSION:
ME is a reliable technique to diagnose villous atrophy.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Atrophy
/
Biopsy
/
Female
/
Humans
/
Male
/
Image Enhancement
/
Celiac Disease
/
Sensitivity and Specificity
/
Duodenoscopy
/
Adult
Type of study:
Diagnostic study
/
Prognostic study
Language:
English
Year:
2007
Type:
Article
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