Prevalence of antibodies to hepatitis C virus in HBsAg negative hemodialysis patients.
Article
in English
| IMSEAR
| ID: sea-64137
ABSTRACT
The prevalence of hepatitis C virus (HCV) infection was estimated in a 14-month study using anti-C100-3 antibody assay in 31 HBsAg negative patients on maintenance hemodialysis (MHD) for > or = 3 months. One and three patients respectively had ALT elevation and anti-HCV positivity at entry. During MHD (mean period of follow up 9.9 mo), 11 (35.5%) patients had, on fortnightly estimation, ALT elevation which lasted for < or = 6 months in seven patients and for > 6 months in four. Fourteen (45.2%) patients had anti-HCV (including the three positive at entry). There was no significant difference in frequency of anti-HCV positivity in patients with normal and elevated ALT (57.1% and 42.9% respectively). The number of blood transfusions and duration of MHD were similar in anti-HCV positive and anti-HCV negative patients. We conclude that our MHD patients have a high frequency of hepatitis and anti-HCV positivity, and these may not be related to blood transfusions.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Female
/
Humans
/
Male
/
Hepatitis Antibodies
/
Prospective Studies
/
Renal Dialysis
/
Hepatitis C
/
Hepacivirus
/
Hepatitis C Antibodies
/
Adult
Type of study:
Observational study
/
Prevalence study
/
Risk factors
Language:
English
Year:
1992
Type:
Article
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