A two-stage clinical trial of Phyllanthus amarus in hepatitis B carriers: failure to eradicate the surface antigen.
Article
in English
| IMSEAR
| ID: sea-64387
ABSTRACT
BACKGROUND:
There have been conflicting data in literature about the value of Phyllanthus amarus in treating hepatitis B virus-related disorders.AIM:
To evaluate the role of Phyllanthus amarus in eradication of the virus in hepatitis B carriers.METHODS:
Phyllanthus amarus was administered to 30 asymptomatic carriers of hepatitis B surface antigen (HBsAg) in a dosage of 250 to 500 mg thrice daily for 4 to 8 weeks.RESULTS:
None of the 30 subjects cleared HBsAg. Phyllanthus amarus was well tolerated, with no clinical side effects or changes in the organ profiles for safety evaluation.CONCLUSION:
Phyllanthus amarus is not effective in clearing HBsAg in asymptomatic carriers of the antigen.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Plants, Medicinal
/
Humans
/
Male
/
Carrier State
/
Adult
/
Hepatitis B
/
Hepatitis B Surface Antigens
/
India
/
Medicine, Traditional
Country/Region as subject:
Asia
Language:
English
Year:
1994
Type:
Article
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