Percutaneous sonography-guided fine needle aspiration biopsy of colonoscopic biopsy-negative colonic lesions.
Article
in English
| IMSEAR
| ID: sea-64751
ABSTRACT
BACKGROUND:
Pre-operative tissue diagnosis with colonoscopy is not always possible in patients with colonic lesions.OBJECTIVE:
To study the usefulness and efficacy of percutaneous ultrasound-guided aspiration biopsy of colonic lesions.METHODS:
Fifty consecutive patients with colonic lesions in whom colonoscopic brush cytology and biopsy were either negative or the lesion was not accessible on colonoscopy on two attempts, underwent percutaneous ultrasound-guided fine-needle aspiration biopsy. The results were compared with surgical findings.RESULTS:
Fine-needle aspiration biopsy revealed adenocarcinoma in 40 patients; one had lymphoma, 2 had tuberculosis, 2 had abscess and 5 patients had negative aspiration. Forty-eight patients (excluding 2 with tuberculosis) underwent laparotomy and the diagnoses on aspiration biopsy were confirmed. Of the 5 negative aspirations, 3 had adenocarcinoma, one had tuberculosis and one intussusception. Thus, we had sensitivity of 91.8%, specificity of 100%, predictive value of positive results 100%, predictive value of negative results 20%, and percentage of false negative results 8.1%. Two patients developed complications--hemorrhage into the peritoneum and sepsis due to perforation at the site of aspiration; both survived after surgery.CONCLUSION:
Percutaneous ultrasound-guided aspiration biopsy may be attempted for diagnosis of colonic lesions in situations where it may be the only means of obtaining a cytological diagnosis before surgery.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Biopsy, Needle
/
Female
/
Humans
/
Male
/
Adenocarcinoma
/
Predictive Value of Tests
/
Ultrasonography
/
Sensitivity and Specificity
/
Colonoscopy
/
Colon
Type of study:
Diagnostic study
/
Prognostic study
Language:
English
Year:
1999
Type:
Article
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