Infliximab in the treatment of ulcerative colitis with toxic megacolon.
Article
in English
| IMSEAR
| ID: sea-65170
ABSTRACT
Toxic megacolon is a gastrointestinal emergency requiring prompt management to avoid fatal outcome. Although a majority of patients respond to conservative treatment, those not responding have been treated with intravenous cyclosporine or emergency surgery. Infliximab has been tried in patients with severe steroid-refractory ulcerative colitis. We report the successful use of this drug in the management of toxic megacolon in a 48-year-old woman not responding to the routine measures and who refused surgery.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Humans
/
Male
/
Colitis, Ulcerative
/
Megacolon, Toxic
/
Middle Aged
/
Antibodies, Monoclonal
Language:
English
Year:
2004
Type:
Article
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