Age-related prevalence of Helicobacter pylori antibodies in Indian subjects.
Article
in English
| IMSEAR
| ID: sea-65224
ABSTRACT
OBJECTIVE:
To determine the age-related prevalence of Helicobacter pylori antibodies in Indian subjects without upper gastrointestinal symptoms. MATERIAL ANDMETHODS:
Sera of 340 subjects without any upper gastrointestinal complaints were screened for IgG and IgA Helicobacter pylori antibodies by the ELISA technique.RESULTS:
The prevalence of IgG and IgA antibodies was 22%, 56% and 87% and 48%, 58% and 83% in 0-4, 5-9 and 10-19 year age groups respectively; thereafter it remained almost constant upto fifth decade. A significant fall in IgG and IgA prevalence was observed from fifth to seventh decades.CONCLUSION:
Our data indicate that in India exposure to Helicobacter pylori occurs early in life and is widespread; about 83% of the population is exposed to Helicobacter pylori during the first two decades of life. The comparable prevalence rates of IgG antibodies to Helicobacter pylori and hepatitis A virus, in different age groups, in India and in the West, suggest a feco-oral mode of transmission for Helicobacter pylori.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Aged
/
Female
/
Humans
/
Male
/
Enzyme-Linked Immunosorbent Assay
/
Seroepidemiologic Studies
/
Child
/
Child, Preschool
/
Helicobacter pylori
/
Adolescent
Type of study:
Prevalence study
/
Risk factors
Country/Region as subject:
Asia
Language:
English
Year:
1994
Type:
Article
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