Dilatation of radiation-induced esophageal strictures under sublingual buprenorphine analgesia: a pilot study.
Article
in English
| IMSEAR
| ID: sea-65420
ABSTRACT
BACKGROUND:
Pain during dilatation of radiation strictures is a troublesome complaint. There is little information on sedation and analgesia during this procedure. We performed a pilot study to compare the analgesic efficacy of sublingual buprenorphine and intravenous pentazocine during dilatation of radiation-induced esophageal strictures.METHODS:
Thirty-one patients with esophageal cancer who had radiation-induced strictures were randomized to receive either buprenorphine 0.2 mg sublingually two hours before dilatation (n = 17) or pentazocine 30 mg intravenously five minutes before dilatation (n = 14). Dilatation was considered successful if it could be performed to 12 mm diameter or more. Pain experienced during dilatation was graded as mild, moderate or severe.RESULTS:
Sixteen patients in the buprenorphine group and 12 in the pentazocine group were dilated to > 12 mm size (p = ns). Twelve and nine patients respectively in the two groups experienced mild or no pain; ten and six patients had minor side-effects (p = ns).CONCLUSION:
Buprenorphine is useful for sedoanalgesia during dilatation of radiation-induced strictures of the esophagus.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Pentazocine
/
Radiation Injuries
/
Aged
/
Buprenorphine
/
Female
/
Humans
/
Male
/
Esophageal Neoplasms
/
Administration, Sublingual
/
Pilot Projects
Type of study:
Controlled clinical trial
/
Diagnostic study
/
Observational study
Language:
English
Year:
1997
Type:
Article
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