Plasma concentrations of lipid peroxidation products in children with acute leukaemia.
Indian J Med Sci
;
2001 Apr; 55(4): 215-7
Article
in English
| IMSEAR
| ID: sea-65851
ABSTRACT
Acute leukaemia is the most common childhood malignancy. The cause of leukaemia is not known in most of the cases and of late free radicals have been implicated in the pathogenesis of leukaemia. The degree of lipid peroxidation was studied in the present study as a marker of disease activity in 15 patients of acute lymphoblastic leukaemia and 20 healthy age and sex matched individuals served as control. Serum malonaldehyde (MDA) levels were increased in leukaemia and were higher in the active phase of disease as compared to those in remission, Hence, serum MDA estimation in leukaemia can be of help in diagnosis and to predict the chances of relapse.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Humans
/
Lipid Peroxidation
/
Biomarkers, Tumor
/
Child
/
Disease Progression
/
Precursor Cell Lymphoblastic Leukemia-Lymphoma
/
Malondialdehyde
Language:
English
Journal:
Indian J Med Sci
Year:
2001
Type:
Article
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