Evaluation of safety and efficacy of azithromycin in lower respiratory tract infections (LRTI)
Article
in English
| IMSEAR
| ID: sea-66618
ABSTRACT
Azithromycin was given to 55 cases of lower respiratory tract infections in the doses of 500 mg on day 1, followed by 250 mg on days 2-5. It produced bacteriological cure in 70.8% patients and clinical cure or improvement in 69.09% of patients. 4.27% of patients had throat colonisation with new organisms, of which 9.09% needed a second antibiotic. The drug was well tolerated and minor side effects were noted. Gastrointestinal disturbances (16.36%) headache and giddiness (14.55%), rash (3.64%) were the noted side effects. Reduction of platelet count by 50% occurred in 12.29% of the cases compared to 0.2% reported earlier. But this thrombocytopenia was clinically not significant, as it did not cause any symptoms.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Respiratory Tract Infections
/
Female
/
Humans
/
Male
/
Adolescent
/
Treatment Outcome
/
Azithromycin
/
Evaluation Studies as Topic
/
India
/
Anti-Bacterial Agents
Type of study:
Diagnostic study
/
Evaluation studies
Country/Region as subject:
Asia
Language:
English
Year:
1996
Type:
Article
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